Various monoclonal antibodies have been developed to block c-Met/HGF signaling pathways, some of which competitively bind to c-Met, and the others are served as traps for c-Met, preventing ligand attachment and dimerization of c-Met [168]
Cryo-EM grid preparation was similar for all samples
2000, 33: S47-58
For example, the mutation of a highly conserved serine residue in the MBL of monovalent metal specific regulators to a cysteine, based on its presence in divalent metal regulators, resulted in variants capable of sensing both Hg II as well as the monovalent coinage metals (Figure 24B)
Lung cancer-targeting peptides with multi-subtype indication for combinational drug delivery and molecular imaging
[DOI] [PubMed] [Google Scholar] 13.Kakinen A, Jiang Y, Davis TP, Teesalu T, Saarma M